synthesis of 2-amino-4hydroxy-1h-pyrrole-3-carbonitrile from glycine under microwave irradiation
Authors
abstract
reaction of glycin with malononitrile afforded respective pyrrole. pyrrole is one of the heterocyclic compounds with very important biological activities. heterocycles are extremely important because of their wide range of applications that goes from their use as pharmaceuticals and agrochemicals to dyestuffs and additives. in this view, it was proposed to synthesize pyrrole-3-carbonitrile derivative. an efficient one-step protocol has been developed to make new molecules of this family. an expeditious synthesis of derivatives pyrrole has been developed by reacting malononitrile and glycine derivatives using a microwave. the structures of synthesized were assigned on the basis of ir and 1h nmr spectroscopy data
similar resources
Synthesis of 2-Amino-4hydroxy-1H-Pyrrole-3-Carbonitrile from Glycine Under Microwave Irradiation
Reaction of Glycin with Malononitrile afforded respective Pyrrole. Pyrrole is one of the heterocyclic compounds with very important biological activities. Heterocycles are extremely important because of their wide range of applications that goes from their use as pharmaceuticals and agrochemicals to dyestuffs and additives. In this view, it was proposed to synthesize pyrrole-3-carbonitrile deri...
full textSynthesis of 2-Amino-4hydroxy-1H-Pyrrole-3-Carbonitrile from Glycine Under Microwave Irradiation
Reaction of Glycin with Malononitrile afforded respective Pyrrole. Pyrrole is one of the heterocyclic compounds with very important biological activities. Heterocycles are extremely important because of their wide range of applications that goes from their use as pharmaceuticals and agrochemicals to dyestuffs and additives. In this view, it was proposed to synthesize pyrrole-3-carbonitrile deri...
full text4-(2,3-Dimethoxyphenyl)-1H-pyrrole-3-carbonitrile
The asymmetric unit of the title compound, C(13)H(12)N(2)O(2), obtained in a search for analogs of the fungicide fludioxonil [systematic name: 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile], contains two independent mol-ecules, A and B. The benzene and pyrrole rings are inclined to each other at 38.5 (1) and 29.3 (1)° in mol-ecules A and B, respectively. In the crystal, bifurc...
full text3-Amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile
In the title compound, C20H14N2O, the phenyl ring is almost normal to the naphthalene ring system with a dihedral angle of 86.72 (9)°. The 4H-pyran ring fused with the naphthalene ring system has a boat conformation. In the crystal, mol-ecules are linked into a helical supra-molecular chain along the b axis via N-H⋯N hydrogen bonds. The chains are consolidated into a three-dimensional architect...
full text1-(2-Hydroxyethyl)-3-[(2-hydroxyethyl)amino]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
There are four molecules in the asymmetric unit of the title compound, C(16)H(17)N(3)O(4), in which the dihedral angles between the indole ring system and maleimide ring are 4.5 (3), 8.3 (3), 8.4 (2) and 10.4 (2)°. In the crystal, mol-ecules are linked by numerous N-H⋯O and O-H⋯O hydrogen bonds, generating a three-dimensional network.
full textZrP2O7 nanoparticles as a robust and efficient catalyst for the synthesis of 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones under microwave irradiation
ZrP2O7 nanoparticles have been used as an efficient catalyst for the preparation of 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones by a simple one-pot four-component reaction of phenyl hydrazines, ethyl acetoacetate ,β-naphthol and benzaldehydes under microwave irradiation in good to excellent yields. When the reaction was carried out using ZrOCl2.8H2O, ZrO2 and ZrP2O7 NPs as the catalyst, the pr...
full textMy Resources
Save resource for easier access later
Journal title:
international journal of advanced biological and biomedical researchPublisher: casrp publishing company
ISSN 2383-2762
volume 1
issue 11 2013
Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023